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sparsentan will reduce the extent or outcome of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep an eye on. Sparsentan (a CYP2C19 inducer) decreases publicity of CYP2C19 substrates and minimizes efficacy connected to these substrates.apalutamide will lessen the level or outcome of modafinil by impacting hepatic/intestinal

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